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In this PDC2008 talk, Chuck Lenzmeier - the Architect in Azure team explains how the Virtual Images of OS works in the Azure cloud data centers. His Bio in PDC2008 says that Chuck has been with Microsoft since 1989, and worked on all versions of Windows from NT 3.1 to Vista. The below video really helps to understand how the Virtual Images are being managed to achieve Windows Azure manage while retaining absolute compatibility with existing OS, Software and Applications.
His co-speaker Frederick Smith from Microsoft explained the other aspects of Windows Azure.